Synthesis and Evaluation of [(11)C]7-Halogen-2-Phenyl Isoindolone Derivatives: Potential PET Radioligands for in vivo Imaging of 5-HT(2)(C) Receptors

The serotonin 5-HT(2)(C) receptor (5-HT(2)(C)R) is abundantly expressed throughout the central nervous system, and involved in a variety of neuroendocrine and neurobehavioral processes. The development of a selective radioligand that will enable in vivo imaging and quantification of 5-HT(2)(C)R dens...

Descripción completa

Detalles Bibliográficos
Autores principales: Zeng, Fanxing, Nye, Jonathon A., Voll, Ronald J., Mun, Jiyoung, Goodman, Mark M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8661056/
https://www.ncbi.nlm.nih.gov/pubmed/34899169
http://dx.doi.org/10.3389/fnins.2021.766320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8661056/
https://www.ncbi.nlm.nih.gov/pubmed/34899169
http://dx.doi.org/10.3389/fnins.2021.766320

Ejemplares similares