Chromothripsis in Chronic Lymphocytic Leukemia: A Driving Force of Genome Instability

Chromothripsis represents a mechanism of massive chromosome shattering and reassembly leading to the formation of derivative chromosomes with abnormal functions and expression. It has been observed in many cancer types, importantly, including chronic lymphocytic leukemia (CLL). Due to the associated...

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Detalles Bibliográficos
Autores principales: Zavacka, Kristyna, Plevova, Karla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8661134/
https://www.ncbi.nlm.nih.gov/pubmed/34900721
http://dx.doi.org/10.3389/fonc.2021.771664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8661134/
https://www.ncbi.nlm.nih.gov/pubmed/34900721
http://dx.doi.org/10.3389/fonc.2021.771664

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