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Chromothripsis in Chronic Lymphocytic Leukemia: A Driving Force of Genome Instability
Chromothripsis represents a mechanism of massive chromosome shattering and reassembly leading to the formation of derivative chromosomes with abnormal functions and expression. It has been observed in many cancer types, importantly, including chronic lymphocytic leukemia (CLL). Due to the associated...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8661134/ https://www.ncbi.nlm.nih.gov/pubmed/34900721 http://dx.doi.org/10.3389/fonc.2021.771664 |