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Genetic Variation of G6PD and CYP2D6: Clinical Implications on the Use of Primaquine for Elimination of Plasmodium vivax

Primaquine, an 8-aminoquinoline, is the only medication approved by the World Health Organization to treat the hypnozoite stage of Plasmodium vivax and P. ovale malaria. Relapse, triggered by activation of dormant hypnozoites in the liver, can occur weeks to years after primary infection, and provid...

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Detalles Bibliográficos
Autores principales: Stewart, Alexandra G. A., Zimmerman, Peter A., McCarthy, James S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8661410/
https://www.ncbi.nlm.nih.gov/pubmed/34899347
http://dx.doi.org/10.3389/fphar.2021.784909