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Identification of TGFβ signaling as a regulator of interneuron neurogenesis in a human pluripotent stem cell model

Cortical interneurons are GABAergic inhibitory cells that connect locally in the neocortex and play a pivotal role in shaping cortical network activities. Dysfunction of these cells is believed to lead to runaway excitation underlying seizure-based diseases, such as epilepsy, autism and schizophreni...

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Detalles Bibliográficos
Autores principales: Cruz Santos, Maria, Li, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8661503/
https://www.ncbi.nlm.nih.gov/pubmed/34956651
http://dx.doi.org/10.1042/NS20210020