The PI3K Inhibitor XH30 Enhances Response to Temozolomide in Drug-Resistant Glioblastoma via the Noncanonical Hedgehog Signaling Pathway

Glioblastoma multiforme (GBM) is the most common malignant tumor of the central nervous system. Temozolomide (TMZ)–based adjuvant treatment has improved overall survival, but clinical outcomes remain poor; TMZ resistance is one of the main reasons for this. Here, we report a new phosphatidylinositid...

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Detalles Bibliográficos
Autores principales: Ji, Ming, Zhang, Zhihui, Lin, Songwen, Wang, Chunyang, Jin, Jing, Xue, Nina, Xu, Heng, Chen, Xiaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662317/
https://www.ncbi.nlm.nih.gov/pubmed/34899305
http://dx.doi.org/10.3389/fphar.2021.749242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662317/
https://www.ncbi.nlm.nih.gov/pubmed/34899305
http://dx.doi.org/10.3389/fphar.2021.749242

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