The Lung Elastin Matrix Undergoes Rapid Degradation Upon Adult Loss of Hox5 Function

Hox genes encode transcription factors that are critical for embryonic skeletal patterning and organogenesis. The Hoxa5, Hoxb5, and Hoxc5 paralogs are expressed in the lung mesenchyme and function redundantly during embryonic lung development. Conditional loss-of-function of these genes during postn...

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Detalles Bibliográficos
Autores principales: Li, Mu-Hang, Marty-Santos, Leilani M., van Ginkel, Paul R., McDermott, Aubrey E., Rasky, Andrew J., Lukacs, Nicholas W., Wellik, Deneen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662386/
https://www.ncbi.nlm.nih.gov/pubmed/34901011
http://dx.doi.org/10.3389/fcell.2021.767454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662386/
https://www.ncbi.nlm.nih.gov/pubmed/34901011
http://dx.doi.org/10.3389/fcell.2021.767454

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