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Inhibiting YAP in Endothelial Cells From Entering the Nucleus Attenuates Blood-Brain Barrier Damage During Ischemia-Reperfusion Injury

Blood-brain barrier (BBB) damage is a critical event in ischemic stroke, contributing to aggravated brain damage. Endothelial cell form a major component of the BBB, but its regulation in stroke has yet to be clarified. We investigated the function of Yes-associated protein 1 (YAP) in the endotheliu...

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Detalles Bibliográficos
Autores principales: Gong, Shuaishuai, Ma, Huifen, Zheng, Fan, Huang, Juan, Zhang, Yuanyuan, Yu, Boyang, Li, Fang, Kou, Junping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662521/
https://www.ncbi.nlm.nih.gov/pubmed/34899341
http://dx.doi.org/10.3389/fphar.2021.777680