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Site-Specific Labeling of Endogenous Proteins Using CoLDR Chemistry
[Image: see text] Chemical modifications of native proteins can affect their stability, activity, interactions, localization, and more. However, there are few nongenetic methods for the installation of chemical modifications at a specific protein site in cells. Here we report a covalent ligand direc...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662641/ https://www.ncbi.nlm.nih.gov/pubmed/34817989 http://dx.doi.org/10.1021/jacs.1c06167 |