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Site-Specific Labeling of Endogenous Proteins Using CoLDR Chemistry

[Image: see text] Chemical modifications of native proteins can affect their stability, activity, interactions, localization, and more. However, there are few nongenetic methods for the installation of chemical modifications at a specific protein site in cells. Here we report a covalent ligand direc...

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Detalles Bibliográficos
Autores principales: Reddi, Rambabu N., Rogel, Adi, Resnick, Efrat, Gabizon, Ronen, Prasad, Pragati Kishore, Gurwicz, Neta, Barr, Haim, Shulman, Ziv, London, Nir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662641/
https://www.ncbi.nlm.nih.gov/pubmed/34817989
http://dx.doi.org/10.1021/jacs.1c06167