Activation of SGK1.1 Upregulates the M-current in the Presence of Epilepsy Mutations

In the central nervous system, the M-current plays a critical role in regulating subthreshold electrical excitability of neurons, determining their firing properties and responsiveness to synaptic input. The M-channel is mainly formed by subunits Kv7.2 and Kv7.3 that co-assemble to form a heterotetr...

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Detalles Bibliográficos
Autores principales: Martin-Batista, Elva, Manville, Rían W., Rivero-Pérez, Belinda, Bartolomé-Martín, David, Alvarez de la Rosa, Diego, Abbott, Geoffrey W., Giraldez, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662703/
https://www.ncbi.nlm.nih.gov/pubmed/34899186
http://dx.doi.org/10.3389/fnmol.2021.798261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662703/
https://www.ncbi.nlm.nih.gov/pubmed/34899186
http://dx.doi.org/10.3389/fnmol.2021.798261

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