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Two Duplicated Ptpn6 Homeologs Cooperatively and Negatively Regulate RLR-Mediated IFN Response in Hexaploid Gibel Carp

Src homology region 2 domain-containing phosphatase 1 (SHP1), encoded by the protein tyrosine phosphatase nonreceptor type 6 (ptpn6) gene, belongs to the family of protein tyrosine phosphatases (PTPs) and participates in multiple signaling pathways of immune cells. However, the mechanism of SHP1 in...

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Detalles Bibliográficos
Autores principales: Tong, Jin-Feng, Zhou, Li, Li, Shun, Lu, Long-Feng, Li, Zhuo-Cong, Li, Zhi, Gan, Rui-Hai, Mou, Cheng-Yan, Zhang, Qi-Ya, Wang, Zhong-Wei, Zhang, Xiao-Juan, Wang, Yang, Gui, Jian-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662705/
https://www.ncbi.nlm.nih.gov/pubmed/34899743
http://dx.doi.org/10.3389/fimmu.2021.780667