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Single-Cell Chemistry of Photoactivatable Platinum Anticancer Complexes

[Image: see text] The Pt(IV) prodrug trans, trans, trans-[Pt(pyridine)(2)(N(3))(2)(OH)(2)] (Pt1) and its coumarin derivative trans, trans, trans-[Pt(pyridine)(2)(N(3))(2)(OH)(coumarin-3-carboxylate)] (Pt2) are promising agents for photoactivated chemotherapy. These complexes are inert in the dark bu...

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Detalles Bibliográficos
Autores principales: Bolitho, Elizabeth M., Sanchez-Cano, Carlos, Shi, Huayun, Quinn, Paul D., Harkiolaki, Maria, Imberti, Cinzia, Sadler, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662725/
https://www.ncbi.nlm.nih.gov/pubmed/34808054
http://dx.doi.org/10.1021/jacs.1c08630