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Caspase-1 Inhibitor Reduces Pyroptosis Induced by Brain Death in Kidney

Brain death (BD) induces an organ-level inflammatory response. However, the underlying mechanisms have not been fully elucidated. Here, we investigated the role of caspase-1-mediated pyroptosis in BD-induced kidney injury in rats. A BD model was established in Sprague-Dawley rats. The rats were intr...

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Detalles Bibliográficos
Autores principales: Liu, Weifeng, Yang, Dongjing, Shi, Jihua, Wen, Peihao, Zhang, Jiakai, Wang, Zhihui, Hu, Bowen, Shi, Xiaoyi, Cao, Shengli, Guo, Wenzhi, Zhang, Shuijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662726/
https://www.ncbi.nlm.nih.gov/pubmed/34901142
http://dx.doi.org/10.3389/fsurg.2021.760989