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A Comparison Between 12 Versus 20 Weeks of Trimethoprim-sulfamethoxazole as Oral Eradication Treatment for Melioidosis: An Open-label, Pragmatic, Multicenter, Non-inferiority, Randomized Controlled Trial

BACKGROUND: Treatment of melioidosis comprises intravenous drugs for at least 10 days, followed by oral trimethoprim-sulfamethoxazole (TMP-SMX) for 12 to 20 weeks. Oral TMP-SMX is recommended for 12 weeks in Australia and 20 weeks in Thailand. METHODS: For this open-label, pragmatic, multicenter, no...

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Detalles Bibliográficos
Autores principales: Anunnatsiri, Siriluck, Chaowagul, Wipada, Teparrukkul, Prapit, Chetchotisakd, Ploenchan, Tanwisaid, Kittisak, Khemla, Supphachoke, Narenpitak, Surapong, Pattarapongsin, Moragot, Kongsawasd, Wirod, Pisuttimarn, Pornrith, Thipmontree, Wilawan, Mootsikapun, Piroon, Chaisuksant, Seksan, Chierakul, Wirongrong, Day, Nicholas P J, Limmathurotsakul, Direk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662794/
https://www.ncbi.nlm.nih.gov/pubmed/32725199
http://dx.doi.org/10.1093/cid/ciaa1084