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A Comparison Between 12 Versus 20 Weeks of Trimethoprim-sulfamethoxazole as Oral Eradication Treatment for Melioidosis: An Open-label, Pragmatic, Multicenter, Non-inferiority, Randomized Controlled Trial
BACKGROUND: Treatment of melioidosis comprises intravenous drugs for at least 10 days, followed by oral trimethoprim-sulfamethoxazole (TMP-SMX) for 12 to 20 weeks. Oral TMP-SMX is recommended for 12 weeks in Australia and 20 weeks in Thailand. METHODS: For this open-label, pragmatic, multicenter, no...
Autores principales: | Anunnatsiri, Siriluck, Chaowagul, Wipada, Teparrukkul, Prapit, Chetchotisakd, Ploenchan, Tanwisaid, Kittisak, Khemla, Supphachoke, Narenpitak, Surapong, Pattarapongsin, Moragot, Kongsawasd, Wirod, Pisuttimarn, Pornrith, Thipmontree, Wilawan, Mootsikapun, Piroon, Chaisuksant, Seksan, Chierakul, Wirongrong, Day, Nicholas P J, Limmathurotsakul, Direk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662794/ https://www.ncbi.nlm.nih.gov/pubmed/32725199 http://dx.doi.org/10.1093/cid/ciaa1084 |
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