DISE/6mer seed toxicity-a powerful anti-cancer mechanism with implications for other diseases

micro(mi)RNAs are short noncoding RNAs that through their seed sequence (pos. 2–7/8 of the guide strand) regulate cell function by targeting complementary sequences (seed matches) located mostly in the 3′ untranslated region (3′ UTR) of mRNAs. Any short RNA that enters the RNA induced silencing comp...

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Detalles Bibliográficos
Autores principales: Haluck-Kangas, Ashley, Patel, Monal, Paudel, Bidur, Vaidyanathan, Aparajitha, Murmann, Andrea E., Peter, Marcus E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662895/
https://www.ncbi.nlm.nih.gov/pubmed/34893072
http://dx.doi.org/10.1186/s13046-021-02177-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662895/
https://www.ncbi.nlm.nih.gov/pubmed/34893072
http://dx.doi.org/10.1186/s13046-021-02177-1

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