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Protect Effects of Seafood-Derived Plasmalogens Against Amyloid-Beta (1–42) Induced Toxicity via Modulating the Transcripts Related to Endocytosis, Autophagy, Apoptosis, Neurotransmitter Release and Synaptic Transmission in SH-SY5Y Cells

To investigate the underlying mechanisms of decreased plasmalogens (Pls) levels in neurodegenerative diseases, here the effects of seafood-derived Pls on undifferentiated and differentiated human SH-SY5Y neuroblastoma cells exposed to amyloid-β(1–42) was analyzed. Transcriptional profiles indicated...

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Detalles Bibliográficos
Autores principales: Feng, Junli, Song, Gongshuai, Shen, Qing, Chen, Xi, Wang, Qingcheng, Guo, Shunyuan, Zhang, Manman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662987/
https://www.ncbi.nlm.nih.gov/pubmed/34899276
http://dx.doi.org/10.3389/fnagi.2021.773713