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Protect Effects of Seafood-Derived Plasmalogens Against Amyloid-Beta (1–42) Induced Toxicity via Modulating the Transcripts Related to Endocytosis, Autophagy, Apoptosis, Neurotransmitter Release and Synaptic Transmission in SH-SY5Y Cells
To investigate the underlying mechanisms of decreased plasmalogens (Pls) levels in neurodegenerative diseases, here the effects of seafood-derived Pls on undifferentiated and differentiated human SH-SY5Y neuroblastoma cells exposed to amyloid-β(1–42) was analyzed. Transcriptional profiles indicated...
Autores principales: | Feng, Junli, Song, Gongshuai, Shen, Qing, Chen, Xi, Wang, Qingcheng, Guo, Shunyuan, Zhang, Manman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662987/ https://www.ncbi.nlm.nih.gov/pubmed/34899276 http://dx.doi.org/10.3389/fnagi.2021.773713 |
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