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Induction and Maturation of Hepatocyte-Like Cells In Vitro: Focus on Technological Advances and Challenges
Limited by the poor proliferation and restricted sources of adult hepatocytes, there is an urgent need to find substitutes for proliferation and cultivation of mature hepatocytes in vitro for use in disease treatment, drug approval, and toxicity testing. Hepatocyte-like cells (HLCs), which originate...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8662991/ https://www.ncbi.nlm.nih.gov/pubmed/34901010 http://dx.doi.org/10.3389/fcell.2021.765980 |