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Efficacy and safety of as-needed albuterol/budesonide versus albuterol in adults and children aged ≥4 years with moderate-to-severe asthma: rationale and design of the randomised, double-blind, active-controlled MANDALA study

INTRODUCTION: Uncontrolled asthma is associated with substantial morbidity. While fast-acting bronchodilators provide quick relief from asthma symptoms, their use as rescue fails to address the underlying inflammation. Combining a short-acting beta(2)-agonist, such as albuterol (salbutamol), with an...

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Detalles Bibliográficos
Autores principales: Chipps, Bradley E, Albers, Frank C, Reilly, Laurence, Johnsson, Eva, Cappelletti, Christy, Papi, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663093/
https://www.ncbi.nlm.nih.gov/pubmed/34887317
http://dx.doi.org/10.1136/bmjresp-2021-001077