NETs decorated with bioactive IL-33 infiltrate inflamed tissues and induce IFN-α production in patients with SLE

IL-33, a nuclear alarmin released during cell death, exerts context-specific effects on adaptive and innate immune cells, eliciting potent inflammatory responses. We screened blood, skin, and kidney tissues from patients with systemic lupus erythematosus (SLE), a systemic autoimmune disease driven b...

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Detalles Bibliográficos
Autores principales: Georgakis, Spiros, Gkirtzimanaki, Katerina, Papadaki, Garyfalia, Gakiopoulou, Hariklia, Drakos, Elias, Eloranta, Maija-Leena, Makridakis, Manousos, Kontostathi, Georgia, Zoidakis, Jerome, Baira, Eirini, Rönnblom, Lars, Boumpas, Dimitrios T., Sidiropoulos, Prodromos, Verginis, Panayotis, Bertsias, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663547/
https://www.ncbi.nlm.nih.gov/pubmed/34554930
http://dx.doi.org/10.1172/jci.insight.147671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663547/
https://www.ncbi.nlm.nih.gov/pubmed/34554930
http://dx.doi.org/10.1172/jci.insight.147671

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