Early IL-10 promotes vasculature-associated CD4(+) T cells unable to control Mycobacterium tuberculosis infection

Cytokine-producing CD4(+) T cells play a crucial role in the control of Mycobacterium tuberculosis infection; however, there is a delayed appearance of effector T cells in the lungs following aerosol infection. The immunomodulatory cytokine IL-10 antagonizes control of M. tuberculosis infection thro...

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Detalles Bibliográficos
Autores principales: Ferreira, Catarina M., Barbosa, Ana Margarida, Barreira-Silva, Palmira, Silvestre, Ricardo, Cunha, Cristina, Carvalho, Agostinho, Rodrigues, Fernando, Correia-Neves, Margarida, Castro, António G., Torrado, Egídio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663558/
https://www.ncbi.nlm.nih.gov/pubmed/34554927
http://dx.doi.org/10.1172/jci.insight.150060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663558/
https://www.ncbi.nlm.nih.gov/pubmed/34554927
http://dx.doi.org/10.1172/jci.insight.150060

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