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The small RNA mascRNA differentially regulates TLR-induced proinflammatory and antiviral responses

MALAT1-associated small cytoplasmic RNA (mascRNA) is a highly conserved transfer RNA–like (tRNA-like) noncoding RNA whose function remains largely unknown. We show here that this small RNA molecule played a role in the stringent control of TLR-mediated innate immune responses. mascRNA inhibited acti...

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Detalles Bibliográficos
Autores principales: Sun, Tao, Wei, Chunxue, Wang, Daoyong, Wang, Xuxu, Wang, Jiao, Hu, Yuqing, Mao, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663567/
https://www.ncbi.nlm.nih.gov/pubmed/34582376
http://dx.doi.org/10.1172/jci.insight.150833