αVβ8 integrin targeting to prevent posterior capsular opacification

Fibrotic posterior capsular opacification (PCO), a major complication of cataract surgery, is driven by transforming growth factor–β (TGF-β). Previously, αV integrins were found to be critical for the onset of TGF-β–mediated PCO in vivo; however, the functional heterodimer was unknown. Here, β8 inte...

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Detalles Bibliográficos
Autores principales: Shihan, Mahbubul H., Novo, Samuel G., Wang, Yan, Sheppard, Dean, Atakilit, Amha, Arnold, Thomas D., Rossi, Nicole M., Faranda, Adam P., Duncan, Melinda K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663568/
https://www.ncbi.nlm.nih.gov/pubmed/34554928
http://dx.doi.org/10.1172/jci.insight.145715

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663568/
https://www.ncbi.nlm.nih.gov/pubmed/34554928
http://dx.doi.org/10.1172/jci.insight.145715

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