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DNA damage is overcome by TRIP13 overexpression during cisplatin nephrotoxicity

Cisplatin is a commonly used chemotherapeutic agent to treat a wide array of cancers that is frequently associated with toxic injury to the kidney due to oxidative DNA damage and perturbations in cell cycle progression leading to cell death. In this study, we investigated whether thyroid receptor in...

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Detalles Bibliográficos
Autores principales: Hama, Taketsugu, Nagesh, Prashanth K.B., Chowdhury, Pallabita, Moore, Bob M., Yallapu, Murali M., Regner, Kevin R., Park, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663775/
https://www.ncbi.nlm.nih.gov/pubmed/34806647
http://dx.doi.org/10.1172/jci.insight.139092