Cargando…

YY1 regulation by miR-124-3p promotes Th17 cell pathogenicity through interaction with T-bet in rheumatoid arthritis

Th17 cells are involved in rheumatoid arthritis (RA) pathogenesis. Our previous studies have revealed that transcription factor Yin Yang 1 (YY1) plays an important role in the pathogenic mechanisms of RA. However, whether YY1 has any role in Th17 cell pathogenicity and what molecular regulatory mech...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Jinpiao, Tang, Jifeng, Lin, Junyu, He, Yujue, Yu, Ziqing, Jiang, Renquan, Yang, Bin, Ou, Qishui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663781/
https://www.ncbi.nlm.nih.gov/pubmed/34806650
http://dx.doi.org/10.1172/jci.insight.149985