Tumor-propagating side population cells are a dynamic subpopulation in undifferentiated pleomorphic sarcoma

Sarcomas contain a subpopulation of tumor-propagating cells (TPCs) with enhanced tumor-initiating and self-renewal properties. However, it is unclear whether the TPC phenotype in sarcomas is stable or a dynamic cell state that can derive from non-TPCs. In this study, we utilized a mouse model of und...

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Detalles Bibliográficos
Autores principales: Tang, Yuning Jackie, Puviindran, Vijitha, Xiang, Yu, Yahara, Yasuhito, Zhang, Hongyuan, Nadesan, Puviindran, Diao, Yarui, Kirsch, David G., Alman, Benjamin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663789/
https://www.ncbi.nlm.nih.gov/pubmed/34618689
http://dx.doi.org/10.1172/jci.insight.148768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663789/
https://www.ncbi.nlm.nih.gov/pubmed/34618689
http://dx.doi.org/10.1172/jci.insight.148768

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