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Mutations in DISC1 alter IP(3)R and voltage-gated Ca(2+) channel functioning, implications for major mental illness
Disrupted in Schizophrenia 1 (DISC1) participates in a wide variety of developmental processes of central neurons. It also serves critical roles that underlie cognitive functioning in adult central neurons. Here we summarize DISC1’s general properties and discuss its use as a model system for unders...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663806/ https://www.ncbi.nlm.nih.gov/pubmed/34956649 http://dx.doi.org/10.1042/NS20180122 |