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Mutations in DISC1 alter IP(3)R and voltage-gated Ca(2+) channel functioning, implications for major mental illness

Disrupted in Schizophrenia 1 (DISC1) participates in a wide variety of developmental processes of central neurons. It also serves critical roles that underlie cognitive functioning in adult central neurons. Here we summarize DISC1’s general properties and discuss its use as a model system for unders...

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Detalles Bibliográficos
Autores principales:	Rittenhouse, Ann R., Ortiz-Miranda, Sonia, Jurczyk, Agata
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663806/ https://www.ncbi.nlm.nih.gov/pubmed/34956649 http://dx.doi.org/10.1042/NS20180122

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