The small molecule SERCA activator CDN1163 increases energy metabolism in human skeletal muscle cells

BACKGROUND AND OBJECTIVE: A number of studies have highlighted muscle-specific mechanisms of thermogenesis involving futile cycling of Ca(2+) driven by sarco (endo)plasmic reticulum Ca(2+)-ATPase (SERCA) and generating heat from ATP hydrolysis to be a promising strategy to counteract obesity and met...

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Detalles Bibliográficos
Autores principales: Mengeste, Abel M., Lund, Jenny, Katare, Parmeshwar, Ghobadi, Roya, Bakke, Hege G., Lunde, Per Kristian, Eide, Lars, Mahony, Gavin O’, Göpel, Sven, Peng, Xiao-Rong, Kase, Eili Tranheim, Thoresen, G. Hege, Rustan, Arild C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663964/
https://www.ncbi.nlm.nih.gov/pubmed/34909682
http://dx.doi.org/10.1016/j.crphar.2021.100060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663964/
https://www.ncbi.nlm.nih.gov/pubmed/34909682
http://dx.doi.org/10.1016/j.crphar.2021.100060

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