Progress towards a clinically-successful ATR inhibitor for cancer therapy

The DNA damage response (DDR) is now known to play an important role in both cancer development and its treatment. Targeting proteins such as ATR (Ataxia telangiectasia mutated and Rad3-related) kinase, a major regulator of DDR, has demonstrated significant therapeutic potential in cancer treatment,...

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Detalles Bibliográficos
Autores principales: Barnieh, Francis M., Loadman, Paul M., Falconer, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663972/
https://www.ncbi.nlm.nih.gov/pubmed/34909652
http://dx.doi.org/10.1016/j.crphar.2021.100017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8663972/
https://www.ncbi.nlm.nih.gov/pubmed/34909652
http://dx.doi.org/10.1016/j.crphar.2021.100017

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