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A narrative review of genetic factors affecting fluoropyrimidine toxicity

OBJECTIVE: Our objective is to document progress in developing personalized therapy with fluoropyrimidine drugs (FPs) to improve outcomes for cancer patients and to identify areas requiring further investigation. BACKGROUND: FPs including 5-fluorouracil (5-FU), are among the most widely used drugs f...

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Detalles Bibliográficos
Autor principal: Gmeiner, William H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664072/
https://www.ncbi.nlm.nih.gov/pubmed/34901834
http://dx.doi.org/10.21037/pcm-21-17