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Tmprss6-ASO as a tool for the treatment of Polycythemia Vera mice

Polycythemia Vera (PV) is a chronic myeloproliferative neoplasm resulting from an acquired driver mutation in the JAK2 gene of hematopoietic stem and progenitor cells resulting in the overproduction of mature erythrocytes and abnormally high hematocrit, in turn leading to thromboembolic complication...

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Detalles Bibliográficos
Autores principales: Casu, Carla, Liu, Alison, De Rosa, Gianluca, Low, Audrey, Suzuki, Aae, Sinha, Sayantani, Ginzburg, Yelena Z., Abrams, Charles, Aghajan, Mariam, Guo, Shuling, Rivella, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664179/
https://www.ncbi.nlm.nih.gov/pubmed/34890402
http://dx.doi.org/10.1371/journal.pone.0251995