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Ultrarapid cryo-arrest of living cells on a microscope enables multiscale imaging of out-of-equilibrium molecular patterns

Imaging molecular patterns in cells by fluorescence micro- or nanoscopy has the potential to relate collective molecular behavior to cellular function. However, spatial and spectroscopic resolution is fundamentally limited by motional blur caused by finite photon fluxes and photobleaching. At physio...

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Detalles Bibliográficos
Autores principales: Huebinger, Jan, Grecco, Hernan, Masip, Martín E., Christmann, Jens, Fuhr, Günter R., Bastiaens, Philippe I. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664253/
https://www.ncbi.nlm.nih.gov/pubmed/34890224
http://dx.doi.org/10.1126/sciadv.abk0882