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The nuclear transcription factor, TAF7, is a cytoplasmic regulator of protein synthesis

The TFIID component, TAF7, has been extensively characterized as essential for transcription and is critical for cell proliferation and differentiation. Here, we report that TAF7 is a previously unknown RNA chaperone that contributes to the regulation of protein synthesis. Mechanistically, TAF7 bind...

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Detalles Bibliográficos
Autores principales: Cheng, Dan, Semmens, Kevin, McManus, Elizabeth, Chen, Qingrong, Meerzaman, Daoud, Wang, Xiantao, Hafner, Markus, Lewis, Brian A., Takahashi, Hidehisa, Devaiah, Ballachanda N., Gegonne, Anne, Singer, Dinah S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664259/
https://www.ncbi.nlm.nih.gov/pubmed/34890234
http://dx.doi.org/10.1126/sciadv.abi5751