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A far-red light–inducible CRISPR-Cas12a platform for remote-controlled genome editing and gene activation
The CRISPR-Cas12a has been harnessed as a powerful tool for manipulating targeted gene expression. The possibility to manipulate the activity of CRISPR-Cas12a with a more precise spatiotemporal resolution and deep tissue permeability will enable targeted genome engineering and deepen our understandi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664267/ https://www.ncbi.nlm.nih.gov/pubmed/34890237 http://dx.doi.org/10.1126/sciadv.abh2358 |