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A far-red light–inducible CRISPR-Cas12a platform for remote-controlled genome editing and gene activation

The CRISPR-Cas12a has been harnessed as a powerful tool for manipulating targeted gene expression. The possibility to manipulate the activity of CRISPR-Cas12a with a more precise spatiotemporal resolution and deep tissue permeability will enable targeted genome engineering and deepen our understandi...

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Detalles Bibliográficos
Autores principales: Wang, Xinyi, Dong, Kaili, Kong, Deqiang, Zhou, Yang, Yin, Jianli, Cai, Fengfeng, Wang, Meiyan, Ye, Haifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664267/
https://www.ncbi.nlm.nih.gov/pubmed/34890237
http://dx.doi.org/10.1126/sciadv.abh2358