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Concomitant activation of GLI1 and Notch1 contributes to racial disparity of human triple negative breast cancer progression

Mortality from triple negative breast cancer (TNBC) is significantly higher in African American (AA) women compared to White American (WA) women emphasizing ethnicity as a major risk factor; however, the molecular determinants that drive aggressive progression of AA-TNBC remain elusive. Here, we dem...

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Detalles Bibliográficos
Autores principales: Siddharth, Sumit, Parida, Sheetal, Muniraj, Nethaji, Hercules, Shawn, Lim, David, Nagalingam, Arumugam, Wang, Chenguang, Gyorffy, Balazs, Daniel, Juliet M, Sharma, Dipali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664295/
https://www.ncbi.nlm.nih.gov/pubmed/34889737
http://dx.doi.org/10.7554/eLife.70729