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A Network-Centric Framework for the Evaluation of Mutual Exclusivity Tests on Cancer Drivers

One of the key concepts employed in cancer driver gene identification is that of mutual exclusivity (ME); a driver mutation is less likely to occur in case of an earlier mutation that has common functionality in the same molecular pathway. Several ME tests have been proposed recently, however the cu...

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Detalles Bibliográficos
Autores principales: Ahmed, Rafsan, Erten, Cesim, Houdjedj, Aissa, Kazan, Hilal, Yalcin, Cansu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664367/
https://www.ncbi.nlm.nih.gov/pubmed/34899838
http://dx.doi.org/10.3389/fgene.2021.746495