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Identification of essential genes in Caenorhabditis elegans through whole-genome sequencing of legacy mutant collections
It has been estimated that 15%–30% of the ∼20,000 genes in C. elegans are essential, yet many of these genes remain to be identified or characterized. With the goal of identifying unknown essential genes, we performed whole-genome sequencing on complementation pairs from legacy collections of matern...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664450/ https://www.ncbi.nlm.nih.gov/pubmed/34550348 http://dx.doi.org/10.1093/g3journal/jkab328 |