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Identification of essential genes in Caenorhabditis elegans through whole-genome sequencing of legacy mutant collections

It has been estimated that 15%–30% of the ∼20,000 genes in C. elegans are essential, yet many of these genes remain to be identified or characterized. With the goal of identifying unknown essential genes, we performed whole-genome sequencing on complementation pairs from legacy collections of matern...

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Detalles Bibliográficos
Autores principales: Li-Leger, Erica, Feichtinger, Richard, Flibotte, Stephane, Holzkamp, Heinke, Schnabel, Ralf, Moerman, Donald G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664450/
https://www.ncbi.nlm.nih.gov/pubmed/34550348
http://dx.doi.org/10.1093/g3journal/jkab328