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Effectiveness and Cardiac Safety of Bedaquiline-Based Therapy for Drug-Resistant Tuberculosis: A Prospective Cohort Study

BACKGROUND: Bedaquiline improves treatment outcomes in patients with rifampin-resistant (RR) tuberculosis but prolongs the QT interval and carries a black-box warning from the US Food and Drug Administration. The World Health Organization recommends that all patients with RR tuberculosis receive a r...

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Detalles Bibliográficos
Autores principales: Brust, James C M, Gandhi, Neel R, Wasserman, Sean, Maartens, Gary, Omar, Shaheed V, Ismail, Nazir A, Campbell, Angela, Joseph, Lindsay, Hahn, Alexandria, Allana, Salim, Hernandez-Romieu, Alfonso C, Zhang, Chenshu, Mlisana, Koleka, Viljoen, Charle A, Zalta, Benjamin, Ebrahim, Ismaeel, Franczek, Meghan, Master, Iqbal, Ramangoaela, Limpho, te Riele, Julian, Meintjes, Graeme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664482/
https://www.ncbi.nlm.nih.gov/pubmed/33882121
http://dx.doi.org/10.1093/cid/ciab335