Allele-specific suppression in Caenorhabditis elegans reveals details of EMS mutagenesis and a possible moonlighting interaction between the vesicular acetylcholine transporter and ERD2 receptors

A missense mutant, unc-17(e245), which affects the Caenorhabditis elegans vesicular acetylcholine transporter UNC-17, has a severe uncoordinated phenotype, allowing efficient selection of dominant suppressors that revert this phenotype to wild-type. Such selections permitted isolation of numerous su...

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Detalles Bibliográficos
Autores principales: Mathews, Eleanor A, Stroud, Dave, Mullen, Gregory P, Gavriilidis, Gavriil, Duerr, Janet S, Rand, James B, Hodgkin, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Neurogenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664489/
https://www.ncbi.nlm.nih.gov/pubmed/33914877
http://dx.doi.org/10.1093/genetics/iyab065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664489/
https://www.ncbi.nlm.nih.gov/pubmed/33914877
http://dx.doi.org/10.1093/genetics/iyab065

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