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Allele-specific suppression in Caenorhabditis elegans reveals details of EMS mutagenesis and a possible moonlighting interaction between the vesicular acetylcholine transporter and ERD2 receptors
A missense mutant, unc-17(e245), which affects the Caenorhabditis elegans vesicular acetylcholine transporter UNC-17, has a severe uncoordinated phenotype, allowing efficient selection of dominant suppressors that revert this phenotype to wild-type. Such selections permitted isolation of numerous su...
Autores principales: | Mathews, Eleanor A, Stroud, Dave, Mullen, Gregory P, Gavriilidis, Gavriil, Duerr, Janet S, Rand, James B, Hodgkin, Jonathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664489/ https://www.ncbi.nlm.nih.gov/pubmed/33914877 http://dx.doi.org/10.1093/genetics/iyab065 |
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