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Smooth-threshold multivariate genetic prediction incorporating gene–environment interactions
We propose a genetic prediction modeling approach for genome-wide association study (GWAS) data that can include not only marginal gene effects but also gene–environment (GxE) interaction effects—i.e., multiplicative effects of environmental factors with genes rather than merely additive effects of...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664495/ https://www.ncbi.nlm.nih.gov/pubmed/34849749 http://dx.doi.org/10.1093/g3journal/jkab278 |