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Smooth-threshold multivariate genetic prediction incorporating gene–environment interactions

We propose a genetic prediction modeling approach for genome-wide association study (GWAS) data that can include not only marginal gene effects but also gene–environment (GxE) interaction effects—i.e., multiplicative effects of environmental factors with genes rather than merely additive effects of...

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Detalles Bibliográficos
Autores principales: Ueki, Masao, Tamiya, Gen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664495/
https://www.ncbi.nlm.nih.gov/pubmed/34849749
http://dx.doi.org/10.1093/g3journal/jkab278