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VDA-RWLRLS: An anti-SARS-CoV-2 drug prioritizing framework combining an unbalanced bi-random walk and Laplacian regularized least squares()

BACKGROUND: A new coronavirus disease named COVID-19, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is rapidly spreading worldwide. However, there is currently no effective drug to fight COVID-19. METHODS: In this study, we developed a Virus-Drug Association (VDA) identific...

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Detalles Bibliográficos
Autores principales: Shen, Ling, Liu, Fuxing, Huang, Li, Liu, Guangyi, Zhou, Liqian, Peng, Lihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664497/
https://www.ncbi.nlm.nih.gov/pubmed/34902608
http://dx.doi.org/10.1016/j.compbiomed.2021.105119