Extracellular Vesicles Released from Neprilysin Gene-Modified Human Umbilical Cord-Derived Mesenchymal Stem Cell Enhance Therapeutic Effects in an Alzheimer's Disease Animal Model

Alzheimer's disease (AD) animal studies have reported that mesenchymal stem cells (MSCs) have therapeutic effects; however, clinical trial results are controversial. Neprilysin (NEP) is the main cleavage enzyme of β-amyloid (Aβ), which plays a major role in the pathology and etiology of AD. We...

Descripción completa

Detalles Bibliográficos
Autores principales: Jeong, HyeJu, Kim, Ok Joon, Oh, Seung-Hun, Lee, Sanghoon, Reum Lee, Han A., Lee, Kee Ook, Lee, Boo-Yong, Kim, Nam Keun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664527/
https://www.ncbi.nlm.nih.gov/pubmed/34899919
http://dx.doi.org/10.1155/2021/5548630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664527/
https://www.ncbi.nlm.nih.gov/pubmed/34899919
http://dx.doi.org/10.1155/2021/5548630

Ejemplares similares