p53 Inhibition Protects against Neuronal Ischemia/Reperfusion Injury by the p53/PRAS40/mTOR Pathway

The underlying mechanisms of cerebral ischemia/reperfusion (I/R) injury are unclear. Within this study, we aimed to explore whether p53 inhibition exerts protective effects via the p53/PRAS40/mTOR pathway after stroke and its potential mechanism. Both an in vitro oxygen-glucose deprivation (OGD) mod...

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Detalles Bibliográficos
Autores principales: Zhao, Jianlan, Dong, Yinhui, Chen, Xingyu, Xiao, Xiao, Tan, Bo, Chen, Gong, Hu, Jin, Qi, Dashi, Li, Xiaomu, Xie, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664552/
https://www.ncbi.nlm.nih.gov/pubmed/34900085
http://dx.doi.org/10.1155/2021/4729465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664552/
https://www.ncbi.nlm.nih.gov/pubmed/34900085
http://dx.doi.org/10.1155/2021/4729465

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