Treatment With the CSF1R Antagonist GW2580, Sensitizes Microglia to Reactive Oxygen Species

Microglia activation and proliferation are hallmarks of many neurodegenerative disorders and may contribute to disease pathogenesis. Neurons actively regulate microglia survival and function, in part by secreting the microglia mitogen interleukin (IL)-34. Both IL-34 and colony stimulating factor (CS...

Descripción completa

Detalles Bibliográficos
Autores principales: Soto-Diaz, Katiria, Vailati-Riboni, Mario, Louie, Allison Y., McKim, Daniel B., Gaskins, H. Rex, Johnson, Rodney W., Steelman, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664563/
https://www.ncbi.nlm.nih.gov/pubmed/34899694
http://dx.doi.org/10.3389/fimmu.2021.734349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664563/
https://www.ncbi.nlm.nih.gov/pubmed/34899694
http://dx.doi.org/10.3389/fimmu.2021.734349

Ejemplares similares