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TORC1 signaling modulates Cdk8-dependent GAL gene expression in Saccharomyces cerevisiae

Cdk8 of the RNA polymerase II mediator kinase complex regulates gene expression by phosphorylating sequence-specific transcription factors. This function is conserved amongst eukaryotes, but the signals and mechanisms regulating Cdk8 activity and phosphorylation of its substrates are unknown. Full i...

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Detalles Bibliográficos
Autores principales: Horvath, Riley, Hawe, Nicole, Lam, Cindy, Mestnikov, Konstantin, Eji-Lasisi, Mariam, Rohde, John, Sadowski, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8664586/
https://www.ncbi.nlm.nih.gov/pubmed/34849833
http://dx.doi.org/10.1093/genetics/iyab168